2023
Epidemiology of Modic changes in dogs: Prevalence, possible risk factors, and association with spinal phenotypes. Beukers M, Grinwis GCM, Vernooij JCM, van der Hoek L, Tellegen AR, Meij BP, Veraa S, Samartzis D, Tryfonidou MA, Bach FC. JOR Spine. 2023 Jul 21;6(3):e1273.
Notochordal cell-derived matrix inhibits MAPK signaling in the degenerative disc environment. Laagland LT, Bach FC, Riemers FM, Erdmann G, Braun TS, van den Akker GGH, Schmitz TC, Creemers LB, Sachse C,Le Maitre CL, Welting TJM, Ito K, Templin MF, Tryfonidou MA. Eur Cell Mater. 2023. 46:57-90
Semi-synthetic degradable notochordal cell-derived matrix hydrogel for use in degenerated intervertebral discs: Initial in vitro characterization. Schmitz TC, van Genabeek B, Pouderoijen MJ, Janssen HM, van Doeselaar M, Crispim JF, Tryfonidou MA, Ito K. J Biomed Mater Res A. 2023 Dec;111(12):1903-1915
A Combined Western and Bead-Based Multiplex Platform to Characterize Extracellular Vesicles. van Maanen JC, Bach FC, Braun TS, Giovanazzi A, van Balkom BWM, Templin M, Wauben MHM, Tryfonidou MA. Tissue Eng Part C Methods. 2023 Aug 22
Epidemiology of Modic changes in dogs: Prevalence, possible risk factors, and association with spinal phenotypes. Beukers M, Grinwis GCM, Vernooij JCM, van der Hoek L, Tellegen AR, Meij BP, Veraa S, Samartzis D, Tryfonidou MA, Bach FC. JOR Spine. 2023 Jul 21;6(3):e1273.
Recommendations for intervertebral disc notochordal cell investigation: From isolation to characterization. Williams RJ, Laagland LT, Bach FC, Ward L, Chan W, Tam V, Medzikovic A, Basatvat S, Paillat L, Vedrenne N, Snuggs JW, Poramba-Liyanage DW, Hoyland JA, Chan D, Camus A, Richardson SM, Tryfonidou MA, Le Maitre CL. JOR Spine. 2023 Jul 9;6(3):e1272
Biomechanical evaluation of a novel biomimetic artificial intervertebral disc in canine cervical cadaveric spines. Jacobs CAM, Doodkorte RJP, Kamali SA, Abdelgawad AM, Ghazanfari S, Jockenhoevel S, Arts JJC, Tryfonidou MA, Meij BP, Ito K. JOR Spine. 2023 Feb 21;6(2):e1251
Acetabular rim extension using a personalized titanium implant for treatment of hip dysplasia in dogs: short-term results. Kwananocha I, Magré J, Willemsen K, Weinans H, Sakkers RJB, How T, Verseijden F, Tryfonidou MA, van der Wal BCH, Meij BP. Front Vet Sci. 2023 Apr 20;10:116017
Dynamic loading leads to increased metabolic activity and spatial redistribution of viable cell density in nucleus pulposus tissue. Salzer E, Mouser VHM, Bulsink JA, Tryfonidou MA, Ito K. JOR Spine. 2023 Jan 3;6(1):e1240.
Ex vivo intervertebral disc cultures: degeneration-induction methods and their implications for clinical translation. Salzer E, Schmitz TC, Mouser VH, Vernengo A, Gantenbein B, Jansen JU, Neidlinger-Wilke C, Wilke HJ, Grad S, Le Maitre CL, Tryfonidou MA, Ito K. Eur Cell Mater. 2023 Mar 29;45:88-112.
Responsible innovation in stem cell research: using responsibility as a strategy. Assen LS, Jongsma KR, Isasi R, Utomo L, Tryfonidou MA, Bredenoord AL. Regen Med. 2023 Mar;18(3):275-284
Sustained release of locally delivered celecoxib provides pain relief for osteoarthritis: a proof of concept in dog patients. Tellegen AR, Rudnik-Jansen I, Utomo L, Beukers M, Teske E, van Weeren PR, Karssemakers-Degen N, Mihov G, Thies J, Eijkelkamp N, Creemers LB, Meij BP, Tryfonidou MA. Osteoarthritis Cartilage. Osteoarthritis Cartilage. 2023 Mar;31(3):351-362.
2022
The catabolic-to-anabolic shift seen in the canine osteoarthritic cartilage treated with knee joint distraction occurs after the distraction period. Teunissen M, Meij BP, Snel L, Coeleveld K, Popov-Celeketic J, Ludwig IS, Broere F, Lafeber FPJG, Tryfonidou MA, Mastbergen SC. J Orthop Translat. 2022 Oct 20;38:44-55
Synovial membrane-derived mesenchymal progenitor cells from osteoarthritic joints in dogs possess lower chondrogenic-, and higher osteogenic capacity compared to normal joints. Teunissen M, Ahrens NS, Snel L, Narcisi R, Kamali SA, van Osch GJCM, Meij BP, Mastbergen SC, Sivrabubramaniyan, Tryfonidou MA. Stem Cell Res Ther. 2022 Sep 5;13(1):457. doi: 10.1186/s13287-022-03144-z.
Hyperosmolar expansion medium improves nucleus pulposus cell phenotype. Laagland LT, Bach FC, Creemers LB, Le Maitre CL, Poramba-Liyanage DW, Tryfonidou MA. JOR Spine, e1219.https://doi.org/10.1002/jsp2.121
Detergent-Free Decellularization of Notochordal Cell-Derived Matrix Yields a Regenerative, Injectable, and Swellable Biomaterial. Schmitz TC, van Doeselaar M, Tryfonidou MA, Ito K. ACS Biomater Sci Eng. 2022 Aug 9. doi: 10.1021/acsbiomaterials.2c00790
Roles and responsibilities in stem cell research: a focus group study with stem cell researchers and patients. Assen LS, Jongsma KR, Isasi R, Tryfonidou MA, Bredenoord AL. Regen Med. 2022 Jul;17(7):445-459. doi: 10.2217/rme-2022-0019
Notochordal Cell-Based Treatment Strategies and Their Potential in Intervertebral Disc Regeneration. Bach FC, Poramba-Liyanage DW, Riemers FM, Guicheux J, Camus A, Iatridis JC, Chan D, Ito K, Le Maitre CL, Tryfonidou MA. Front Cell Dev Biol. 2022 Mar 14;9:780749. doi: 10.3389/fcell.2021.780749
Intervertebral disc degeneration in warmblood horses: Histological and biochemical characterization. Bergmann W, de Lest CV, Plomp S, Vernooij JCM, Wijnberg ID, Back W, Gröne A, Delany MW, Caliskan N, Tryfonidou MA, Grinwis GCM. Vet Pathol. 2022 Mar;59(2):284-298. doi: 10.1177/03009858211067463
Injectable Hydrogels for Articular Cartilage and Nucleus Pulposus Repair: Status Quo and Prospects. Zoetebier B, Schmitz TC, Ito K, Karperien M, Tryfonidou MA, Paez JI. Tissue Eng Part A. 2022 Jun;28(11-12):478-499. doi: 10.1089/ten.TEA.2021.0226
2021
A perspective on the ORS Spine Section initiative to develop a multi-species JOR Spine histopathology series. Dahia CL, Engiles JB, Gullbrand SE, Iatridis JC, Lai A, Le Maitre CL, Lotz JC, Masuda K, Séguin CA, Tryfonidou MA. JOR Spine. 2021 Jul 26;4(2):e1165. doi: 10.1002/jsp2.1165
A comprehensive tool box for large animal studies of intervertebral disc degeneration. Lee NN, Salzer E, Bach FC, Bonilla AF, Cook JL, Gazit Z, Grad S, Ito K, Smith LJ, Vernengo A, Wilke HJ, Engiles JB, Tryfonidou MA. JOR Spine. 2021 Jun 14;4(2):e1162. doi: 10.1002/jsp2.1162.
Recognizing the ethical implications of stem cell research: A call for broadening the scope.
Assen LS, Jongsma KR, Isasi R, Tryfonidou MA, Bredenoord AL. Stem Cell Reports. 2021 Jul 13;16(7):1656-1661. doi: 10.1016/j.stemcr.2021.05.021.
Enhanced Extracellular Matrix Breakdown Characterizes the Early Distraction Phase of Canine Knee Joint Distraction. Teunissen M, Miranda Bedate A, Coeleveld K, Riemers FM, Meij BP, Lafeber FPJG, Tryfonidou MA, Mastbergen SC. Cartilage. 2021 May 20:19476035211014595. doi: 10.1177/19476035211014595
Biomechanical effects of a titanium intervertebral cage as a stand-alone device, and in combination with locking plates in the canine caudal cervical spine. Beishuizen R, Reints Bok TE, Teunissen M, van der Veen AJ, Emanuel KS, Tryfonidou MA, Meij BP. Vet Surg. 2021 Jul;50(5):1087-1097. doi: 10.1111/vsu.13657.
Biomechanical effects of a titanium intervertebral cage as a stand-alone device, and in combination with locking plates in the canine caudal cervical spine. Beishuizen R, Reints Bok TE, Teunissen M, van der Veen AJ, Emanuel KS, Tryfonidou MA, Meij BP. Vet Surg. 2021 Jul;50(5):1087-1097. doi: 10.1111/vsu.13657.
Transformed Canine and Murine Mesenchymal Stem Cells as a Model for Sarcoma with Complex Genomics. Franceschini N, Verbruggen B, Tryfonidou MA, Kruisselbrink AB, Baelde H, de Visser KE, Szuhai K, Cleton-Jansen AM, Bovée JVMG. Cancers (Basel). 2021 Mar 5;13(5):1126. doi: 10.3390/cancers13051126
Pituitary tumour types in dogs and cats. Sanders K, Galac S, Meij BP. Vet J. 2021 Apr;270:105623. doi: 10.1016/j.tvjl.2021.105623.
Evaluation of hypophysectomy for treatment of hypersomatotropism in 25 cats. van Bokhorst KL, Galac S, Kooistra HS, Valtolina C, Fracassi F, Rosenberg D, Meij BP. J Vet Intern Med. 2021 Mar;35(2):834-842. doi: 10.1111/jvim.16047.
The lower in vitro chondrogenic potential of canine adipose tissue-derived mesenchymal stromal cells (MSC) compared to bone marrow-derived MSC is not improved by BMP-2 or BMP-6. Teunissen M, Verseijden F, Riemers FM, van Osch GJVM, Tryfonidou MA. Vet J. 2021 Mar;269:105605. doi: 10.1016/j.tvjl.2020.105605.