Are you a motivated and creative MSc student looking for an exciting research internship position?

Project description: we have an internship position within the NC-CHOICE project where we study the extracellular vesicles derived from the nucleus pulposus and their regenerative potential, as a potential therapeutic strategy for intervertebral disc degeneration.

For this internship project, you will perform tissues collection from porcine cadavers, extracellular vesicles isolation, and 3D model cell culture. The aim is to isolate and characterize the extracellular vesicles present within the nucleus pulposus and test their regenerative potential on a 3D model of degenerated intervertebral disc.

You will experience:

• cadaveric tissue collection
• cell and tissue culture techniques
• histological techniques (tissue processing, sectioning, biochemical staining and immunohistochemistry)
• biochemical assays and PCR
• confocal microscopy

Supervisor: Daniele Corraini

Preferred starting date: to be discussed

Duration: at least 6 to 12 months

Eligibility: students enrolled at the GSLS at Utrecht University. Especially suitable for students enrolled in the programs: Regenerative Medicine and Technology (RMT), Drug innovation, Bio Inspired Innovation (BII), or Molecular and Cellular Life Sciences (MCLS), and Cancer, Stem Cells and Developmental Biology (CSBD).

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