New publication: Disc-Derived Induced Pluripotent Stem Cells and Environmental Cues for Nucleus Pulposus Regeneration

Congrats to Lisanne Laagland and colleagues for their latest paper where they explored an alternative for notochordal cells using human induced pluripotent stem cells (iPSC) by comparing cells derived from disc progenitor cells versus blood cells. By combining these cells with an instructive disc-derived matrix, the team achieved better differentiation into healthy, disc-repairing cells. The results highlight the importance of the cells’ original epigenetic memory in supporting effective spinal disc regeneration. Read the whole article here >>